Yevgenya Grinblat

Credentials: Professor

Position title: Developmental Biology, Genetics/Genomics, Neuroscience

Email: ygrinblat@wisc.edu

Phone: 608-265-3219

Address:
219 iBio Research Building

Research Areas
Developmental Biology, Genetics/Genomics, Neuroscience

Lab Page

Research Areas

Developmental Biology, Genetics/Genomics, Neuroscience

Research Interests

  • Genetic control of cranial morphogenesis in vertebrate embryos.
  • Modeling frontonasal dysplasia, coloboma and holoprosencephaly in zebrafish.
  • Gene/environment interactions during cranial morphogenesis.
  • Modeling genetic predisposition to fetal alcohol toxicity in zebrafish.

Recent publications

  • Santistevan, N. J., et al.  (2022) A forward genetic screen identifies a novel role for cacna2d3 in vertebrate habituation learning and startle threshold. PLoS ONE 17(7): e0270903. PMID: 35834485
  • Yoon, B., et al.  (2022). Zebrafish models of Alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye. Biology Open PMID: 35142342
  • Pini, J., et al.  (2020). ALX1-related  Frontonasal Dysplasia Results From Defective Neural Crest Cell Development and  Migration.  EMBO Molecular Medicine, 12:e12013. PMID: 32914578
  • Grinblat, Y. & Lipinski, R. J. (2019). A forebrain undivided: Unleashing model organisms to solve the mysteries of holoprosencephaly. Dev Dyn, 248(8), 626-633. PMID: 30993762
  • Sedykh, I., et al.  (2018) Zebrafish Rfx4 controls dorsal and ventral midline formation in the neural tube. Dev Dyn 247, 650-659.  PMCID: PMC5854527
  • Sedykh, I., et al. (2017). “Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis.” Dev Biol 429, 92-104. PMID: 28689736

Teaching:

  • Zoology 555 – Laboratory in Developmental Biology
  • Zoology 655 – Modeling Neurodevelopmental Disease
  • Neuroscience 765 – Developmental Neuroscience